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Running helps mice slow cancer growth

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Running helps mice slow cancer growth
Mice who spent their free time on a running wheel were better able to shrink tumors (a 50% reduction in tumor size) compared to their less active counterparts. Researchers found that the surge of adrenaline that comes with a high-intensity workout helped to move cancer-killing immune (NK) cells toward lung, liver, or skin tumors implanted into the mice.
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| Categories: | Tags: mice, cancer, running | Comments: (1) | View Count: (1407)
Scientists create mini-brains to study neurological diseases
The brains are grown using stem cells derived from human skin samples.
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| Categories: | Tags: brains, neurological diseases | Comments: (0) | View Count: (1205)
16

Aging shrinks chromosomes

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Aging shrinks chromosomes
A study on human cells reveals how cellular aging affects the 3-D architecture of chromosomes.
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| Categories: | Tags: senescence, genetics & genomics, epigenetics, disease/medicine, chromatin, cell & molecular biology and aging | Comments: (0) | View Count: (1401)
Patient-specific age: the other side of the coin in advanced mesenchymal stem cell therapy
Multipotential mesenchymal stromal cells (MSC) are present as a rare subpopulation within any type of stroma in the body of higher animals. Prominently, MSC have been recognized to reside in perivascular locations, supposedly maintaining blood vessel integrity. During tissue damage and injury, MSC/pericytes become activated, evade from their perivascular niche and are thus assumed to support wound healing and tissue regeneration. In vitro MSC exhibit demonstrated capabilities to differentiate in...
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| Categories: | Tags: vascular niche, cell-based therapy, aging biology, cellular dysfunction, age-associated pathology, regenerative medicine | Comments: (0) | View Count: (1462)
Abrogation of age-induced microRNA-195 rejuvenates the senescent mesenchymal stem cells by reactivating telomerase
Here we present the first evidence that miR-195 overexpressed in old MSCs (OMSCs) induces stem cell senescence deteriorating their regenerative ability by directly deactivating telomerase reverse transcriptase (Tert), and abrogation of miR-195 can reverse stem cell aging.
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| Categories: | Tags: aging, stem cells, miR-195, telomerase, heart | Comments: (0) | View Count: (1549)
Team grows functioning pituitary gland from human embryonic stem cells
When the anterior pituitary gland is damaged—through tumours, infections, or even genetic factors—many different disorders can arise, some of which—like insufficient ACTH—are life threatening.
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| Categories: | Tags: pituitary gland, pituitary gland, human stem cells | Comments: (0) | View Count: (1463)
09

Wait not in vain

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Wait not in vain
After decades of piecemeal progress, the science of cryogenically storing human organs is warming up.
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| Categories: | Tags: cryogenically storing, human organs | Comments: (0) | View Count: (1309)
Physical exercise boosts your brain power in 20 minutes, helps stop brain shrinkage
Scientists have been linking the benefits of physical exercise to brain health for many years, but new research is making it clear that the two aren't just simply related; rather, it is THE relationship.
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| Categories: | Tags: physical exercise, brain, brain shrinkage, brain power | Comments: (1) | View Count: (1711)
09

PRMT7 preserves satellite cell regenerative capacity

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PRMT7 preserves satellite cell regenerative capacity
PRMT7 is required for muscle stem cell self-renewal and regenerative capacity in vivo. PRMT7 deletion causes senescence of activated muscle stem cells. This entry into senescence is associated with persistent expression of p21.
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| Categories: | Tags: PRMT7, muscle regeneration, senescence, aging, DNMT3b, p21CIP1, muscle stem cell | Comments: (0) | View Count: (1575)
09

Delivering genes across the blood-brain barrier

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Delivering genes across the blood-brain barrier
Caltech biologists have developed a vector capable of noninvasive delivery of genetic cargo throughout the adult central nervous system.
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| Categories: | Tags: genes, blood-brain barrier | Comments: (0) | View Count: (1345)
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