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PolarityTE fully regenerated pig skin and hair follicles in third-degree burns.

Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. Aging research has experienced an unprecedented advance over recent years, particularly with the discovery that the rate of aging is controlled, at least to some extent, by genetic pathways and bioch...

A bill may soon grant Texans greater access to unapproved but promising stem cell therapies, Stat News reports. Its passage would make Texas the first state to back the technology, which has not been approved by federal regulators and many experts consider risky.  

Regulatory T cells (Tregs; pronounced 'tee-regs'), a type of immune cell generally associated with controlling inflammation, directly trigger stem cells in the skin to promote healthy hair growth, researchers have discovered. Without these immune cells as partners, the researchers found, the stem cells cannot regenerate hair follicles, leading to baldness.

A team from the Aikenhead Centre for Medical Discovery at St Vincent’s Hospital in Melbourne, Australia has successfully tested its innovative “Biopen.” The 3D bioprinting pen, which can be filled with stem cell hydrogel ink cartridges, was used to repair a sheep’s knee.

Researchers identify transcription factors and environmental conditions necessary to reprogram human and mouse cells into cells that function like hematopoietic stem cells.

The stem cells that produce our blood have been created in the lab for the first time. These could one day be used to treat people who have blood diseases and leukaemia with their own cells, rather than bone marrow transplants from a donor. They could also be used to create blood for transfusions.

Researchers hope to one day use stem cells to heal burns, patch damaged heart tissue, even grow kidneys and other transplantable organs from scratch.

Using CRISPR technology, a team of researchers rewired stem cells' genetic circuits to produce an anti-inflammatory arthritis drug when the cells encounter inflammation. The technique eventually could act as a vaccine for arthritis and other chronic conditions.

Using human skin cells, University of California, Irvine neurobiologists and their colleagues have created a method to generate one of the principle cell types of the brain called microglia, which play a key role in preserving the function of neural networks and responding to injury and disease.