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CRISPR: gene editing is just the beginning

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CRISPR: gene editing is just the beginning
The real power of the biological tool lies in exploring how genomes work.
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| Categories: | Tags: Biological techniques, Epigenetics, Genetics, Non-coding RNAs | Comments: (0) | View Count: (1212)
10

Welcome to the CRISPR zoo

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Welcome to the CRISPR zoo
Birds and bees are just the beginning for a burgeoning technology.
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| Categories: | Tags: Biotechnology, Genetics, Synthetic biology, Society | Comments: (0) | View Count: (1169)
Researchers dig up new molecular details on 'the other type' of stem cells
Scientists reveal that the combination of two molecular signals determines which cells that have already differentiated can regain their stem cell properties.
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| Categories: | Tags: Stem Cells, Skin Cancer, Prostate Cancer, Lymphoma, Immune System, Brain Tumor | Comments: (0) | View Count: (992)
03

The red-hot debate about transmissible Alzheimer's

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The red-hot debate about transmissible Alzheimer's
A controversial study has suggested that the neurodegenerative disease might be transferred from one person to another. Now scientists are racing to find out whether that is true.
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| Categories: | Tags: alzheimer, neurodegenerative disease | Comments: (0) | View Count: (1039)
Popular stem cell techniques deemed safe; unlikely to pass on cancer-causing mutations
A new study shows that the act of creating pluripotent stem cells for clinical use is unlikely to pass on cancer-causing mutations to patients.
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| Categories: | Tags: Stem Cells, Cancer, Skin Cancer, Lymphoma, Prostate Cancer, Brain Tumor | Comments: (0) | View Count: (964)
20

An epigenetic clock controls aging

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An epigenetic clock controls aging
We are accustomed to treating aging as a set of things that go wrong with the body. But for more than twenty years, there has been accumulating evidence that much of the process takes place under genetic control.
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| Categories: | Tags: Senescence, Programmed aging, Epigenetic, Evolution, Life history, Gene expression | Comments: (0) | View Count: (1094)
First drug to reverse Huntington’s disease begins human trials
The new drug, called IONIS-HTTRx, silences the gene known to be responsible for the production of a protein which causes Huntington’s
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| Categories: | Tags: new drug, IONIS-HTTRx, silences the gene, production of a protein, science | Comments: (0) | View Count: (2498)
Scientists have figured out why drug-resistant 'superbugs' are so hard to kill
You may have already heard about the growing problem caused by antibiotic resistance - the spread of superbugs that have evolved to become resistant to the antibiotics we usually attack them with. It's an issue that could have very serious implications for global health and disease if it isn't tackled urgently, and now researchers have made an important step in finding a solution.
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| Categories: | Tags: growing problem, antibiotic resistance, e-coli, science | Comments: (0) | View Count: (1508)
Geriatric Conditions in a Population-Based Sample of Older Homeless Adults
Purpose of the Study: Older homeless adults living in shelters have high rates of geriatric conditions, which may increase their risk for acute care use and nursing home placement. However, a minority of homeless adults stay in shelters and the prevalence of geriatric conditions among homeless adults living in other environments is unknown. We determined the prevalence of common geriatric conditions in a cohort of older homeless adults, and whether the prevalence of these conditions differs acro...
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| Categories: | Tags: Homeless persons, Functional status, Sensory impairment, Cognitive impairment, Epidemiology | Comments: (0) | View Count: (1893)
Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis
Direct induction of induced hepatocytes (iHeps) from fibroblasts holds potential as a strategy for regenerative medicine but until now has only been shown in culture settings. Here, we describe in vivo iHep formation using transcription factor induction and genetic fate tracing in mouse models of chronic liver disease.
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| Categories: | Tags: FOXA3, GATA4, HNF1A, HNF4A, aging, science, regenerative medicine | Comments: (0) | View Count: (1374)
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