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The Hallmarks of Aging

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The Hallmarks of Aging
Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. Aging research has experienced an unprecedented advance over recent years, particularly with the discovery that the rate of aging is controlled, at least to some extent, by genetic pathways and bioch...
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| Categories: | Tags: Aging signs, aging biomarkers, genome, telomeres, epigenetic alterations, proteostasis, nutrients, mitochondrial dysfunction, cell aging, stem cells, intercellular interaction, genetics | Comments: (0) | View Count: (1026)
The FDA just approved a drug that targets cancer by genetic marker, not body parts
On May 23, the US Food and Drug Administration (FDA) granted accelerated approval to pembrolizumab, made by Merck and marketed as Keytruda, for adults and children without remaining treatment alternatives and with metastatic solid tumors identified with a biomarker called microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR).
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| Categories: | Tags: cancer, oncology, biomarkers | Comments: (0) | View Count: (850)