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Preventing age-related decline of gut compartmentalization limits microbiota dysbiosis and extends lifespan
Summary Compartmentalization of the gastrointestinal (GI) tract of metazoans is critical for health. GI compartments contain specific microbiota, and microbiota dysbiosis is associated with intestinal dysfunction. Dysbiosis develops in aging intestines, yet how this relates to changes in GI compartmentalization remains unclear. The Drosophila GI tract is an accessible model to address this question. Here we show that the stomach-like copper cell region (CCR) in the middle midgut controls distri...
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| Categories: | Tags: age-related, compartmentalization, microbiota dysbiosis, lifespan | Comments: (0) | View Count: (1525)
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Drug prevents age related brain changes in rats

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Drug prevents age related brain changes in rats
As brain cells age they lose the fibers that receive neural impulses, a change that may underlie cognitive decline. Researchers at the University of California, Irvine recently found a way to reverse this process in rats. The study was published Feb. 3, 2016 in The Journal of Neuroscience. Researchers caution that more studies are needed, but the findings shed light on the mechanisms of cognitive decline and identify potential strategies to stem it.
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| Categories: | Tags: drag, age-related changes, brain, rats | Comments: (0) | View Count: (1443)
05

Drug prevents key age-related brain change in rats

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Drug prevents key age-related brain change in rats
As brain cells age they lose the fibers that receive neural impulses, a change that may underlie cognitive decline. Researchers at the University of California, Irvine recently found a way to reverse this process in rats. The study was published Feb. 3, 2016 in The Journal of Neuroscience. Researchers caution that more studies are needed, but the findings shed light on the mechanisms of cognitive decline and identify potential strategies to stem it.
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| Categories: | Tags: drug, age-related, rats, brain change | Comments: (0) | View Count: (1385)